![]() ![]() ![]() This study is registered at as #NCT00072761. Hemoglobin concentration and systolic blood pressure are risk factors for SCI in children with SCA and may be therapeutic targets for decreasing the risk of SCI. 030) were statistically significantly associated with an increased risk of an SCI. 001), higher baseline systolic blood pressure ( P =. In a multivariable logistic regression analysis, lower baseline hemoglobin concentration ( P <. The mean age of the participants was 9.1 years, with 413 males (50.7%). SCIs were diagnosed in 30.8% (251 of 814) participants who completed all evaluations and had valid data on all prespecified demographic and clinical covariates. Neuroradiology and neurology committees adjudicated the presence of SCI. In this cross-sectional study, we evaluated the clinical history and baseline laboratory values and performed magnetic resonance imaging of the brain in participants with SCA (HbSS or HbSβ° thalassemia) between the ages of 5 and 15 years with no history of overt stroke or seizures. In the Silent Cerebral Infarct Multi-Center Clinical Trial, we sought to identify risk factors associated with SCI. If you just change your mind, you have to pay the postage and we will refund only upon reception of goods and provided they arrive undamaged and unused.The most common form of neurologic injury in sickle cell anemia (SCA) is silent cerebral infarction (SCI). We will pay the cost of the cancellation unless you or the recipient fails to organise the collection within 21 days of the cancellation and if the reason of cancellation is based on Mind Games' process, ie. You must make sure the goods are available for collection by our carrier who can only collect during the daytime on weekdays (not weekends or Bank Holidays) within 21 days of notifying us of the cancellation.The goods must be unused and nothing must have been opened.Notify us of the cancellation in writing / email within seven working days of delivery.You may cancel your order providing that you follow the following guidelines: In the unlikely event your order arrives broken or damaged, claims should be made by email 48 hours of receipt. Visit us at Mind Games, at 10 karpenisiou str, Nicosia 1077Īll courier deliveries are fully insured. ![]() Write to: Mind Games, PO Box 24984, Nicosia, CYPRUS.At the moment we are still building our on-line shop, the online collection is limited, but updated regularly. Shop online at on your desktop, tablet or mobile.For international orders, outside EU, all local taxes, clearing charges, etc remain responsibility of the buyer. All other orders are sent by express mail services, registered, with tracking numbers. For international deliveries, any orders above 400 Euros are delivered by express courier without an additional cost. Iron, coal, and cotton are three industries which appear in both the original Brass as well as in Brass: Birmingham.ĭELIVERY – LOCAL & INTERNATIONAL Shipping This provides players with the opportunity to score much higher value canals in the first era, and creates interesting strategy with industry placement. Instead of each flipped industry tile giving a static 1 VP to all connected canals and rails, many industries give 0 or even 2 VPs. VPs are counted at the end of each half for the canals, rails and established (flipped) industry tiles.īirmingham features dynamic scoring canals/rails. The game is played over two halves: the canal era (years 1770-1830) and the rail era (years 1830-1870). (This action replaces Double Action Build in original Brass.) Birmingham tells the story of competing entrepreneurs in Birmingham during the industrial revolution, between the years of 1770-1870.Īs in its predecessor, you must develop, build, and establish your industries and network, in an effort to exploit low or high market demands.Įach round, players take turns according to the turn order track, receiving two actions to perform any of the following actions (found in the original game):ġ) Build – Pay required resources and place an industry tile.Ģ) Network – Add a rail / canal link, expanding your network.ģ) Develop – Increase the VP value of an industry.Ĥ) Sell – Sell your cotton, manufactured goods and pottery.ĥ) Loan – Take a £30 loan and reduce your income.īrass: Birmingham also features a new sixth action:Ħ) Scout – Discard three cards and take a wild location and wild industry card. Brass: Birmingham tells the story of competing entrepeneurs in Birmingham during the industrial revolutionīrass: Birmingham is an economic strategy game sequel to Martin Wallace’ 2007 masterpiece, Brass. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |